TūkinoKo te tātai matū ko (C27H30O16•3H2O), he huaora, he pānga ki te whakaiti i te urunga me te pakarukaru o ngā uaua toto, te pupuri me te whakahoki mai i te ngāwari noa o ngā uaua toto. Hei ārai me te rongoā i te toto toto tiketike o te roro; Ka whakamahia hoki te toto retina mate huka me te purpura toto hei kai ārai mate me ngā tae.

Kua wehea kia whā ngā paearu e whai ake nei:

1. Te Mahi NF11: paura kōwhai-kakariki, he tioata angiangi rawa rānei; Kore kakara, kore reka; Ka pōuri te tae i te hau; Ka wera ki te 185-192 ℃, ka huri hei tinana parauri rite ki te gelatin, ā, ka pirau i te 215℃ pea. He wairewa paku ki te etanoru kohua, he wairewa paku ki te wai kohua, he wairewa paku ki te wai matao, he ngāwari ki te wairewa i roto i te waipiro isopropyl me te methanol, kāore e wairewa i roto i te trichloromethane, ether me te benzene; Ka wairewa i roto i te otinga hauwai waikawa kawakore. Ko te tikanga tautuhi ko A: te waikuratanga o te waikawa hauwai ki te quercetin, ko tōna ira rewa ko 312℃B: te maturuturunga o te waikura kapuro whero. C: Ko te tāpiri i te otinga hauwai waikawa konutai he karaka kōwhai D: ko te otinga etanoru me te otinga hauwai konupora he parauri kakariki E: ko te otinga etanoru me te waikawa hauwai me te konupora he whero haere te ihirangi: ≥95.0%(UV)(mā ngā hua maroke)

Te whakahekenga taumaha maroke: 5.5% ~ 9.0%

Te toenga tahunga ≤0.5%

Koropira ≤0.004%

Tae whero ≤0.004%

Matū e pā ana ki te quercetin ≤5.0%(UV)

Te tapeke o ngā huakita ā-hauora ≤103cfu/g

Te tapeke o te harore me te rewena ≤102cfu/g

Kāore e kitea te Escherichia coli /g

Ngā tikanga rokiroki Penapena ki roto i tētahi ipu ārai-hau, kia matara atu i te mārama.

2. Rutoside Trihydrate EP 9.0: Paura kōwhai, kōwhai-kakariki rānei. Tata kore e wairewa i te wai, wairewa i te methanol, paku wairewa i te etanoru (96%), tata kore e wairewa i te methylene chloride. Wairewa i roto i te otinga hauwai. Ko te tikanga tautuhi penei :A: Ko te mimiti mōrahi i te 257nm me te 358nm, ā, ko te tauwehenga mimiti mōrahi i te 358nm ko 305 ~ 330. B: Me rite te tauira mimiti pūwero ki tērā o te hua tohutoro C: Ka puta ngā ira o te tae me te rahi kotahi i te tūranga e rite ana o te chromatogram o te hua tohutoro D: ka whero te otinga etanoru me te waikawa hauwai me te konutea

Ihirangi 95.0% ~ 101.0% (mā te hua maroke) (whakamātautau)

Makuku 7.5% ~ 9.5% (Cartesian)

Te toenga tahunga ≤0.1%

Kaua te uara mimiti mārama mōrahi o ngā poke whatu i te 450nm ki te 800nm ​​e neke ake i te 0.10

Mea kore e rewa i roto i te methanol ≤3.0%

Matū e pā ana: isoquercetin ≤2.0%, kaempferol-3-rutin ≤2.0%, quercetin ≤2.0%, poke katoa ≤4.0% (HPLC)

Te tapeke o ngā huakita ā-hauora ≤104cfu/g

Te tapeke o te harore me te rewena ≤102cfu/g

Huakita karamu-kino o te au ≤102cfu/g

Kāore e kitea te Escherichia coli /g

Kāore pea e kitea te Salmonella /25g

Ngā tikanga rokiroki: Me noho tawhiti atu i te māramatanga

3. Rutin USP43Ko te tikanga tautuhi ko A: te mimiti mōrahi i te 257nm me te 358nm, ā, ko te tauwehenga mimiti mōrahi i te 358nm ko 305 ~ 33. B: Me rite ngā ira mimiti whero-whero ki te chromatogram o te hua tohutoro. C: Me rite te wā pupuri o te tihi chromatogram ki te hua tohutoro.

Ihirangi 95.0% ~ 101.0% (mā te hua maroke) (whakamātautau)

Makuku 7.5% ~ 9.5% (Cartesian)

Te toenga tahunga ≤0.1%

Kaua te uara mimiti mārama mōrahi o ngā poke whatu i te 450nm ki te 800nm ​​e neke ake i te 0.10

Mea kore e rewa i roto i te methanol ≤3.0%

Ngā matū e pā ana: isoquercetin ≤2.0%, kaempferol-3-rutin ≤2.0%, quercetin ≤2.0%, ētahi atu mono-miscellaneous ≤1.0%, te poke katoa ≤4.0% (HPLC)

Te tapeke o ngā huakita ā-hauora ≤104cfu/g

Te tapeke o te pokepokea ai me te rewena ≤103cfu/g

Kaua e kitea te Escherichia coli /10g

Kaua e kitea te Salmonella /10g

Kua hiritia te āhua rokiroki, ā, kua waiho kia matara atu i te mārama.

4. Paerewa Manatū WS1-49(B)-89 o RutinumHe paura kōwhai, he paura kōwhai-kakariki rānei, he tioata angiangi rawa rānei; Kāore he kakara, kāore he reka; Ka pōuri te tae i te hau; Ka whakamahanatia ki te 185 ~ 192℃ kia huri hei kirikiri parauri. He wairewa paku ki te etanoru kohua, he wairewa paku ki te wai kohua, he wairewa paku ki te wai matao, kāore e wairewa ki te trichloromethane me te ether; Ka wairewa ki te wairewa hauwai kawakore. Ko te tikanga tautuhi ko: A: he waikura kapu whero kua puta. B: Me rite te tauira mimiti whero ki te tauira o te matū whakahaere. C: Ka kitea te mimiti mōrahi i ngā roangaru o te 259±1nm me te 362.5±1nm.

Ihirangi ≥93.0%(UV)(mā te hua maroke)

Te whakahekenga taumaha maroke 5.5% ~ 9.0%

Te toenga tahunga ≤0.3%

Mea kore e rewa i roto i te methanol ≤2.5% (mea kore e rewa i roto i te ethanol)

Matū e pā ana ki te quercetin ≤4.0% (Papa angiangi)

Te tapeke o ngā huakita ā-hauora ≤103cfu/g

Te tapeke o te harore me te rewena ≤102cfu/g

Kāore e kitea te Escherichia coli /g

Kāore e kitea te Salmonella /g

Kua hiritia te āhua rokiroki, ā, kua waiho kia matara atu i te mārama.

Pānga rongoā：

Te mahi ārai-ira kore utu

Ka whakaitihia ngā ngota hāora i roto i te āhua o ngā irahiko takitahi i roto i te pākia o te pūtau, ā, ko ngā iona O i hangaia e te whakaiti i ngā ngota hāora i roto i te āhua o ngā irahiko takitahi ka whakaputa i te H2O2 me ngā rauropi kore paitini ·OH i roto i te tinana, ā, ka pā ki te maeneene o te kiri, ka tere ake hoki te koroheketanga o te kiri. Hei tāpiri, mā te tāpiri i te rutin ki te hua ka taea te tango i ngā momo hāora tauhohe i hangaia e ngā pūtau. Ko te rutin he matū flavonoid, he antioxidant kaha mō te tango i ngā rauropi kore utu. Ka taea e ia te aukati i te tauhohenga mekameka o ngā rauropi kore utu, te aukati i te peroxidation o ngā waikawa ngako polyunsaturated i runga i ngā biofilms, te tango i ngā hua peroxidation lipid, te tiaki i te kounga o ngā biofilms me ngā hanganga pūtau-iti, ā, he mahi nui hoki i roto i te tinana. [2]

Te ārai i te waikura lipid

Ko te peroxidation lipid e pā ana ki tētahi raupapa o ngā tukanga whakapūngao i puta mai i ngā momo hāora tauhohe e whakaeke ana i ngā waikawa ngako polyunsaturated i roto i ngā biofilms. I whakatauhia e Zhu Jianlin me ētahi atu, ā, i tātarihia hoki te mahi SOD i roto i ngā kiore, te ihirangi o te hua peroxidation lipid free-radical MDA, me te ihirangi o Lipofuscin i roto i te ate nui, ā, i kitea he pānga aukati a te rutin ki te peroxidation lipid i roto i ngā kiore kua whakapūngaohia, ā, ka taea te aukati i te hekenga o te kaha antioxidant o te pūnaha antioxidant i roto i ngā kiore i muri i te whakapūngaohia. Ka taea e te rutin te ātete i te hekenga o te kaha antioxidant i puta mai i te hekenga o te estrogen endogenous, ā, he pānga antioxidant. He pānga anti-atherosclerotic te lipoprotein kiato teitei (HDL). Heoi, ko te HDL, pērā i te lipoprotein kiato iti (LDL) me te lipoprotein kiato tino iti (VLDL), ka taea hoki te whakapūngao me te whakarerekē i roto i te vitro. Kia whakapūngaohia te HDL me te whakarerekē ki Ox-HDL, ka pā te atherosclerosis. I rangahauhia e Meng Fang me ētahi atu te pānga o te rutin ki te whakarerekētanga oxidative HDL e te whakarerekētanga oxidative i waenga i te Cu2+ i roto i te vitro. Whakamutunga Ka taea e te rutin te aukati nui i te whakarerekētanga oxidative o te HDL. [2]

Te pānga ātete o te take whakahohe pereti

Ko te pathogenesis o ngā mate maha o te pūnaha manawa me te roro, pērā i te thrombosis, te atherosclerosis, te tauhohenga mumura me te whara o te ischemia-reperfusion free radical, he hononga tata ki te takawaenga o te plateletactivatingfactor (PAF). Nō reira, ko te ārai i te pānga o te PAF he huarahi nui ki te whakamama i ngā mate pūnaha manawa me te roro ischemic. I whakaatuhia e ngā whakamātautau ka taea e te rutin te ārai i te here motuhake o te PAF ki ngā kaiwhakawhiwhi membrane pereti rāpeti e whakawhirinaki ana ki te kukū, te aukati i te piri o te pereti i roto i ngā rāpeti me te pikinga o te kukū Ca2+ kore utu i roto i ngā PMN, e kī ana ko te tikanga o te mahi anti-PAF a te rutin he aukati i te whakahohenga o te kaiwhakawhiwhi PAF, kātahi ka aukati i te tauhohenga i puta mai i te PAF, kia whai wāhi ai ki te tiaki i te pūnaha manawa. I whakaatuhia e ngā hua ko te rutin he kaiwhakawhiwhi PAF. [2]

Te rongoā mō te pancreatitis whakapeka

Ka taea e te rutin te ārai i te hypocalcemia me te whakaiti i te kukū Ca2+ i roto i te kiko repeure. I kitea ka taea e te rutin te whakanui ake i te ihirangi o te phospholipase A2 (PLA2) i roto i te kiko repeure o ngā kiore, e kī ana ka taea e te rutin te aukati i te tukunga me te whakahohenga o te PLA2 i roto i te kiko repeure. Ka taea e te rutin te ārai i te putanga mai o te hypocalcemia i roto i ngā kiore AP, mā te aukati pea i te urunga mai o te Ca2+ me te whakaiti i te taumaha Ca2+ i roto i ngā pūtau kiko repeure, ā, ka whakaiti i te kino pathophysiological ki te AP. [2]

Tohutoro: https://mp.weixin.qq.com

https://xueshu.baidu.com/usercenter/paper

Mō ngā mahi o ia rā, tēnā whakapā mai. Kei te tatari mātou ki a koe i ngā wā katoa.