Ka whakamahia e tō tinana hei whakaputa i te serotonin, he matū e tuku tohu ana i waenga i ngā pūtau io.
Kua honoa te iti o te serotonin ki te pouri, te manukanuka, te raruraru moe, te taumaha, me ētahi atu raruraru hauora (1, 2).
Ka whakanui ake te whakaheke taumaha i te whakaputanga o ngā homoni e hua ai te hiakai. Mā tēnei kare ā-roto o te hiakai tonu ka kore e taea te whakaheke taumaha mō te wā roa (3, 4, 5).
Tērā pea ka ārai te 5-HTP i ēnei homoni e whakaoho ana i te hiakai e pehi ana i te hiahia kai, ā, ka āwhina i a koe ki te whakaiti i tō taumaha (6).
I roto i tētahi rangahau, i tohua matapōkeretia kia whiwhi 5-HTP, placebo rānei, ngā tūroro mate huka e 20 mō ngā wiki e rua. I whakaatuhia e ngā hua ko te hunga i whiwhi 5-HTP i kai i te 435 karori iti iho i ia rā, ki te whakaritea ki te rōpū placebo (7).
Heoi anō, ko te 5-HTP te mea nui hei pehi i te kai warowaihā, e hono ana ki te whakahaere pai ake i te glycemic (7).
He maha atu anō ngā rangahau kua whakaatu mai ka whakanui ake te 5-HTP i te makona me te whakatairanga i te whakahekenga taumaha i roto i te hunga taumaha rawa, momona rānei (8, 9, 10, 11).
Hei tāpiritanga, kua whakaatuhia e ngā rangahau kararehe ka taea e te 5-HTP te whakaiti i te nui o te kai e kainga ana e te ahotea, e te pouri rānei (12, 13).
Tērā pea ka whai hua te 5-HTP ki te whakanui ake i te makona, ka āwhina i a koe ki te kai iti me te whakaiti i tō taumaha.
Ahakoa kāore i te tino mōhiotia te tino take o te pouri, e whakapono ana ētahi kairangahau ka pā te kore taurite o te serotonin ki tō wairua, ka arahi atu ki te pouri (14, 15).
Ina hoki, he maha ngā rangahau iti kua whakaatu ka taea e te 5-HTP te whakaiti i ngā tohu o te pouri. Heoi, e rua o rātou kāore i whakamahi i te placebo hei whakataurite, ā, nā tēnei i whakawhāiti te mana o ā rātou hua (16, 17, 18, 19).
Heoi, he maha ngā rangahau kua whakaatu he kaha ake te pānga o te 5-HTP ki te rongoā i te pouri ina whakamahia ngātahi me ētahi atu matū, rongoā rānei i te wā e whakamahia ana ko ia anake (17, 21, 22, 23).
Hei tāpiritanga, he maha ngā arotake kua whakatau he nui ake ngā rangahau kounga teitei e hiahiatia ana i mua i te tūtohutanga o te 5-HTP mō te rongoā i te pouri (24, 25).
Ka whakanuia e ngā tāpiringa 5-HTP ngā taumata o te serotonin i roto i te tinana, ka taea te whakaora i ngā tohu o te pouri, inā koa ka honoa ki ētahi atu rongoā ārai pouri, rongoā rānei. Heoi, me nui ake ngā rangahau e hiahiatia ana.
Mā te tāpiringa 5-HTP ka pai ake ngā tohu o te fibromyalgia, he mate e tohuhia ana e te mamae o te uaua me te wheua me te ngoikore whānui.
Kāore anō kia mōhiotia he take mō te fibromyalgia i tēnei wā, engari kua honoa te iti o te taumata serotonin ki te mate (26).
Nā tēnei ka whakapono ngā kairangahau he pai pea te whakanui ake i ngā taumata serotonin me ngā tāpiringa 5-HTP ki te hunga whai fibromyalgia (27).
Ina hoki, e whakaatu ana ngā taunakitanga tōmua ka taea e te 5-HTP te whakapai ake i ngā tohu o te fibromyalgia, tae atu ki te mamae o te uaua, ngā raruraru moe, te manukanuka, me te ngenge (28, 29, 30).
Heoi, kāore anō kia nui ngā rangahau kua mahia hei whakatau i ngā whakatau pakari mō te whai huatanga o te 5-HTP ki te whakapai ake i ngā tohu o te fibromyalgia.
Ka whakanui ake te 5-HTP i ngā taumata serotonin i roto i te tinana, ka taea te whakaora i ētahi o ngā tohu o te fibromyalgia. Heoi, me nui ake ngā rangahau e hiahiatia ana.
E kiia ana ka āwhina te 5-HTP ki te rongoā i ngā migraines, he momo ānini e haere tahi ana me te whakapairuaki, ngā raruraru tirohanga rānei.
Ahakoa kei te tautohetia tonutia te take tuturu o ēnei mate, e whakapono ana ētahi kairangahau nā te iti o te taumata o te serotonin i hua mai ai (31, 32).
I whakaritea e tētahi rangahau i roto i te 124 tāngata te kaha o te 5-HTP me te methylergometrine, he rongoā migraine noa, ki te ārai i te migraine headaches (33).
I kitea i roto i tētahi rangahau ko te tango i te 5-HTP i ia rā mō ngā marama e ono i ārai, i whakaiti rānei i te maha o ngā whakaekenga migraine i roto i te 71% o ngā kaiuru (33).
I tētahi atu rangahau mō ngā ākonga 48, i whakaitihia e te 5-HTP te auau o te ānini mā te 70% ki te 11% i roto i te rōpū placebo (34).
Waihoki, he maha atu ngā rangahau kua whakaatu he pai te rongoā a te 5-HTP mō ngā mate pōuri (30, 35, 36).
He mea nui te mahi a te melatonin ki te whakahaere i te moe. Ka tīmata te piki o ōna taumata i te pō hei whakatairanga i te moe, ā, ka tīmata i te ata hei āwhina i a koe ki te oho ake.
Nō reira, mā te tāpiringa 5-HTP ka taea te whakatairanga i te moe mā te whakanui ake i te hanga o te melatonin i roto i te tinana.
I kitea i roto i tētahi rangahau tangata, ko te whakakotahitanga o te 5-HTP me te waikawa gamma-aminobutyric (GABA) i tino whakaiti i te wā e moe ai, i whakanui ake i te roa o te moe, ā, i whakapai ake i te kounga o te moe (37).
He matū karere a GABA e whakatairanga ana i te whakangā. Mēnā ka honoa ki te 5-HTP, tera pea ka whai pānga tahi (37).
Ina hoki, he maha ngā rangahau kararehe me ngā pepeke kua whakaatu ko te 5-HTP ka whakapai ake i te kounga o te moe, ā, he pai ake anō hoki ina honoa ki te GABA (38, 39).
Ahakoa he pai ngā hua o ēnei, nā te kore o ngā rangahau tangata ka uaua ki te taunaki i te 5-HTP hei whakapai ake i te kounga o te moe, ina koa ka whakamahia ko ia anake.
Tērā pea ka pāngia ētahi tāngata e te whakapairuaki, te korere, te ruaki, me te mamae o te puku i te wā e tango ana i ngā tāpiringa 5-HTP. Ka whakawhirinaki ēnei pānga taha ki te horopeta, arā, ka kino haere i te pikinga o te horopeta (33).
Hei whakaiti i ēnei pānga taha, tīmata ki te horopeta o te 50–100 mg e rua ngā wā i te rā, ka whakapiki ake ki te horopeta e tika ana mō ngā wiki e rua (40).
Ka whakanui ake ētahi rongoā i te hanga o te serotonin. Mā te whakakotahi i ēnei rongoā me te 5-HTP ka puta he taumata morearea o te serotonin i roto i te tinana. Ka kiia tēnei ko te serotonin syndrome, he mate ka morearea pea ki te ora (41).
Ko ētahi rongoā ka taea te whakanui ake i ngā taumata serotonin i roto i te tinana ko ētahi rongoā antidepressants, rongoā maremare, rongoā mamae rānei kua tohua.
Nā te mea ka taea hoki e te 5-HTP te whakatairanga i te moe, ka nui rawa te hiamoe mēnā ka tangohia me ngā rongoā whakamoe pēnei i a Klonopin, Ativan, Ambien rānei.
Nā te mea ka pāngia pea koe e ngā taunekeneke kino me ētahi atu rongoā, me kōrero koe ki tō tākuta, ki tō kaiwhakahaere rongoā rānei i mua i te tango i ngā tāpiringa 5-HTP.
I te wā e hoko ana i ngā tāpiringa kai, kimihia ngā hiri NSF, USP rānei e tohu ana i te kounga teitei. He kamupene tuatoru ēnei e kī taurangi ana kei roto i ngā tāpiringa ngā mea kua whakahuatia i runga i te tapanga, ā, kāore he poke.
Tērā pea ka pāngia ētahi tāngata e ngā pānga taha ina tangohia ngā tāpiringa 5-HTP. Me kōrero ki tō tākuta i mua i te tango i te 5-HTP kia mōhio ai koe he haumaru mōu.
He rerekē ēnei tāpiringa i ngā tāpiringa L-tryptophan, ka taea hoki e ēnei te whakanui ake i ngā taumata serotonin (42).
Ko te L-tryptophan he waikawa amino nui e kitea ana i roto i ngā kai whai pūmua pērā i te miraka, te heihei, te mīti, te pīni pīni, me te pīni soya.
I tētahi atu ringa, kāore te 5-HTP e kitea i roto i te kai, ā, ka taea anake te tāpiri atu ki tō kai mā roto i ngā tāpiringa kai (43).
Ka hurihia e tō tinana te 5-HTP hei serotonin, he matū e whakahaere ana i te hiahia kai, te kite mamae, me te moe.
He maha ngā painga o te nui o te serotonin, pērā i te whakaheke taumaha, te whakaora i ngā tohu o te pouri me te fibromyalgia, te whakaiti i te auau o ngā whakaeke migraine, me te moe pai ake.
Kua pāngia ētahi pānga taha iti e te 5-HTP, engari ka taea te whakaiti i ēnei mā te tīmata me ngā horopeta iti ake, me te whakanui haere i te horopeta.
I te mea ka pā kino pea te 5-HTP ki ētahi rongoā, me whakapā atu ki tō tākuta kia mōhio ai he haumaru mōu.
Kei te aro turuki tonu ā mātou tohunga i te ao hauora me te oranga tinana, me te whakahou anō i ā mātou tuhinga ina puta mai ngā mōhiotanga hou.
E whakamahia whānuitia ana te 5-HTP hei tāpiringa hei whakanui ake i ngā taumata serotonin. Ka whakamahia e te roro te serotonin hei whakahaere i te wairua, te hiahia kai, me ētahi atu mahi nui. engari…
Me pēhea te rongoā a Xanax i te pouri? He mea noa te whakamahi i te Xanax hei rongoā i te manukanuka me ngā mate mataku.