Ko te berberine, te berberine hydrochloride rānei, he matū e kitea ana i roto i te maha o ngā tipu. Ka taea e ia te āwhina ki te rongoā i ngā mate pēnei i te mate huka, te cholesterol tiketike me te toto toto tiketike. Heoi, ko ngā pānga taha ko te mamae o te puku me te whakapairuaki.
Kua whakamahia te berberine hei wāhanga o te rongoā tuku iho a Haina me Ayurvedic mō ngā mano tau. He rerekē ngā mahi a te tinana, ā, ka taea e ia te whakarerekē i ngā pūtau o te tinana.
E ai ki ngā rangahau mō te berberine, ka taea e ia te rongoā i ngā momo mate pāwera, tae atu ki te mate huka, te momona, me te mate ngakau. Tērā pea ka pai ake te hauora o te puku.
Ahakoa te āhua haumaru o te berberine, ā, he iti noa ngā pānga taha, me kōrero koe ki tō tākuta i mua i te tango.
He rongoā patu huakita whai hua pea te berberine. I kitea i roto i tētahi rangahau i te tau 2022 ka āwhina te berberine ki te aukati i te tipu o te Staphylococcus aureus.
I kitea e tētahi atu rangahau ka taea e te berberine te kino i te DNA me ngā pūmua o ētahi huakita.
E whakaatu ana ngā rangahau he āhuatanga ārai-mumura tō te berberine, arā, ka āwhina pea ki te rongoā i te mate huka me ētahi atu mate e pā ana ki te mumura.
E ai ki ngā rangahau he pai pea te berberine mō te rongoā i te mate huka. Kua whakaatuhia e ngā rangahau he pānga pai ki:
I kitea i roto i taua tātaritanga anō he pai ake te whai huatanga o te whakakotahitanga o te berberine me te rongoā whakaheke huka toto i te whakamahi takitahi i tētahi o ngā rongoā e rua.
E ai ki tētahi rangahau i te tau 2014, e whakaatu ana te berberine i te pūmanawa hei rongoā pea mō te mate huka, inā koa mō te hunga kāore e taea te tango i ngā rongoā antidiabetic nā te mate ngakau, te ngoikore o te ate, ngā raruraru tākihi rānei.
I kitea e tētahi atu arotake o ngā tuhinga ko te berberine me ngā huringa o te noho i whakaiti i ngā taumata huka toto nui atu i ngā huringa o te noho anake.
Te āhua nei ka whakahohehia e te berberine te pūmua kinase kua whakahohehia e te AMP, e āwhina ana ki te whakahaere i te whakamahinga o te huka toto e te tinana. E whakapono ana ngā kairangahau ka taea e tēnei whakahohenga te āwhina i te rongoā i te mate huka me ngā raruraru hauora e pā ana ki tēnei momo momona me te cholesterol tiketike.
I whakaatuhia e tētahi atu tātaritanga-maha o te tau 2020 ngā whakapainga o te taumaha tinana me ngā tawhā pākia o te tinana, me te kore e pikinga nui o te mahi whākōkī ate.
Heoi, me whakahaere e ngā kaipūtaiao he rangahau matapo-rua nui ake hei whakatau i te haumaru me te whai huatanga o te berberine.
Kōrero ki tō tākuta i mua i te tango i te berberine mō te mate huka. Kāore pea e pai mō te katoa, ā, ka taunekeneke pea me ētahi atu rongoā.
Ka taea e ngā taumata tiketike o te cholesterol me ngā triglycerides lipoprotein iti-kiato (LDL) te whakanui ake i te mōrearea o te mate ngakau me te whiu.
E ai ki ētahi taunakitanga, ka āwhina pea te berberine ki te whakaheke i te cholesterol LDL me ngā triglycerides. E ai ki tētahi arotake, e whakaatu ana ngā rangahau kararehe me te tangata ka whakaheke te berberine i te cholesterol.
Ka āwhina tēnei ki te whakaheke i te LDL, te cholesterol "kino", me te whakapiki i te HDL, te cholesterol "pai".
I kitea i roto i tētahi arotake o ngā tuhinga he pai ake te whai huatanga o te berberine me ngā huringa momo noho ki te rongoā i te cholesterol tiketike i ngā huringa momo noho anake.
E whakapono ana ngā kairangahau he rite tonu te mahi a te berberine ki ngā rongoā whakaheke cholesterol, engari kāore e puta ngā pānga taha ōrite.
I kitea i roto i tētahi arotake o ngā tuhinga he pai ake te whai huatanga o te berberine i te wā e whakamahia ana me ngā rongoā whakaheke toto toto i te wā e whakamahia ana ko ia anake.
Hei tāpiri, ko ngā hua o ngā rangahau kiore e kī ana ka taea e te berberine te whakaroa i te tīmatanga o te toto toto tiketike me te āwhina ki te whakaiti i tōna kaha ina puta te toto toto tiketike.
I roto i tētahi arotake i kōrerohia he nui te whakahekenga taumaha i roto i te hunga e tango ana i te 750 mirikaramu (mg) o te barberry e rua ngā wā i te rā mō ngā marama e 3. He tipu te barberry kei roto he nui te berberine.
I tua atu, i kitea i roto i tētahi rangahau matapo-rua he iti ake te taupū papatipu tinana o te hunga whai mate pāwera i tango i te 200 mg o te barberry e toru ngā wā i te rā.
I kitea e tētahi rōpū e whakahaere ana i tētahi atu rangahau ka taea e te berberine te whakahohe i te kiko ngako parauri. Ka āwhina tēnei kiko i te tinana ki te huri i te kai hei wera tinana, ā, ka āwhina pea te whakanui ake i te whakahohenga ki te rongoā i te momona me te mate pāwera.
E ai ki ētahi rangahau he rite tonu te mahi a te berberine ki te rongoā metformin, e tohua ana e ngā tākuta hei rongoā i te mate huka momo 2. Inaa, tera pea ka taea e te berberine te whakarerekē i ngā huakita o te puku, ka āwhina pea ki te rongoā i te momona me te mate huka.
Ka puta te mate ovarian polycystic (PCOS) ina nui te taumata o ētahi homoni tāne i roto i ngā wāhine. Ko te mate nei he kore taurite o ngā homoni me ngā matūkai ka arahi atu ki te kore tamariki me ētahi atu raruraru hauora.
He maha ngā raruraru e pā ana ki te mate ovary polycystic ka taea e te berberine te whakaoti. Hei tauira, ko te hunga whai PCOS ka pāngia pea e:
I ētahi wā ka tohua e ngā tākuta te metformin, he rongoā mate huka, hei rongoā mō te PCOS. Nā te mea he rite ngā pānga o te berberine ki te metformin, he pai pea hei rongoā mō te PCOS.
I kitea i roto i tētahi arotake pūnaha he pai te berberine mō te rongoā i te mate ovary polycystic me te ātete insulin. Heoi, e kī ana ngā kaituhi me nui ake te rangahau hei whakaū i ēnei pānga.
Ka pāngia pea koe e te berberine e ngā huringa i roto i ngā ngota pūtau, ā, tera pea he painga anō tērā: te whawhai ki te mate pukupuku.
E kī ana tētahi atu rangahau ka āwhina te berberine ki te rongoā i te mate pukupuku mā te aukati i tōna whanaketanga me tōna huringa ora noa. Tērā pea ka whai wāhi anō hoki ki te patu i ngā pūtau mate pukupuku.
I runga i ēnei raraunga, e kī ana ngā kaituhi he rongoā ārai matepukupuku "tino whai hua, haumaru, me te utu tika" te berberine.
Heoi, he mea nui kia mahara ko ngā pānga o te berberine ki ngā pūtau matepukupuku i roto i te taiwhanga anake i akohia e ngā kairangahau, kāore i roto i te tangata.
E ai ki ētahi rangahau i whakaputaina i te tau 2020, mēnā ka āwhina te berberine ki te rongoā i te mate pukupuku, te mumura, te mate huka me ētahi atu mate, tera pea nā ōna pānga pai ki te microbiome o te puku. Kua kitea e ngā kaipūtaiao he hononga i waenga i te microbiome o te puku (ngā koroni o ngā huakita i roto i ngā whekau) me ēnei āhuatanga.
He āhuatanga patu huakita kei roto i te berberine, ā, ka tangohia e ia ngā huakita kino mai i ngā whekau, ā, ka whakatairanga i te tipu o ngā huakita hauora.
Ahakoa e whakaatu ana ngā rangahau i roto i te tangata me ngā kiore he pono pea tēnei, e whakatūpato ana ngā kaipūtaiao me nui ake ngā rangahau hei whakaū i te pānga o te berberine ki te tangata, me te haumaru hoki ki te whakamahi.
E ai ki te American Association of Naturopathic Physicians (AANP) kei te wātea ngā tāpiringa berberine i roto i te puka tāpiringa, i te puka capsule rānei.
E ai ki tā rātou, he maha ngā rangahau e taunaki ana kia tangohia te 900-1500 mg ia rā, engari ko te nuinga o te tangata e tango ana i te 500 mg e toru ngā wā i te rā. Heoi, e akiaki ana te AANP i te tangata kia kōrero ki te tākuta i mua i te tango i te berberine kia tirohia ai mēnā he haumaru te whakamahi me te horopeta ka taea te tango.
Mena ka whakaae te tākuta he haumaru te whakamahi i te berberine, me tirotiro hoki te tangata i te tapanga hua mō ngā tiwhikete tuatoru, pērā i te National Science Foundation (NSF) me te NSF International rānei, e ai ki te AANP.
I kitea e ngā kaituhi o tētahi rangahau i te tau 2018 he rerekē rawa ngā ihirangi o ngā kāpū berberine rerekē, ā, ka ara ake pea tēnei i te whakapoauau mō te haumaru me te horopeta. Kāore i kitea e rātou ko ngā utu teitei ake he tohu i te kounga hua teitei ake.
Kāore te US Food and Drug Administration (FDA) e whakahaere i ngā tāpiringa kai. Kāore he taurangi e haumaru ana, e whai hua ana rānei ngā tāpiringa, ā, kāore e taea te manatoko i te kounga o te hua i ngā wā katoa.
E ai ki ngā kaipūtaiao he maha ngā āhuatanga ōrite o te berberine me te metformin, ā, tera pea ka whai hua ngā mea e rua mō te rongoā i te mate huka momo 2.
Heoi, ki te tohua e te tākuta te metformin mō te tangata, kaua e whakaarohia te berberine hei rongoā kē atu me te kore e kōrero tuatahi ki tā rātou tākuta.
Mā ngā tākuta e tohu te horopeta tika o te metformin mō te tangata i runga i ngā rangahau haumanu. Kāore e taea te mōhio me pēhea te ōrite o ngā tāpiringa ki tēnei nui.
Tērā pea ka taunekeneke a Berberine me te metformin, ā, ka pā ki tō huka toto, ka uaua ai te whakahaere. I roto i tētahi rangahau, ko te tango tahi i te berberine me te metformin ka whakaiti i ngā pānga o te metformin mā te 25%.
Tērā pea ka pai te whakamahi i te berberine hei whakakapi mō te metformin hei whakahaere i te huka toto, engari me nui ake ngā rangahau e hiahiatia ana.
E ai ki te National Center for Complementary and Integrative Health (NCCIH), kāore pea te goldenrod, kei roto nei te berberine, e pāngia kino i roto i te wā poto mēnā ka tangohia e ngā pakeke. Heoi, kāore i te rawaka ngā mōhiohio hei whakaatu he haumaru mō te whakamahinga mō te wā roa.
I roto i ngā rangahau kararehe, i kitea e ngā kaipūtaiao ngā pānga e whai ake nei i runga i te momo kararehe, te nui me te roa o te whakahaerenga:
He mea nui kia kōrero koe ki tō tākuta i mua i te tango i te berberine, i ētahi atu tāpiringa rānei, nā te mea kāore pea i te haumaru, ā, kāore pea e pai mō te katoa. Me mutu tonu te whakamahi a te hunga he mate pāwera ki tētahi hua otaota.